-
订货电话
021-69583055 -
电话订货时间
周一至周五 9:00~17:00 -
电子邮件订货
2025037171@qq.com
上海岚派生物科技有限公司 > 产品类别 > 抗体 > 一抗 >
- 品名:
- 整合素样金属蛋白酶与凝血酶1型-7抗体 (N端抗体)
- 货号:
- hj-1140A
- 英文:
- ADAMTS7(NT)
- 英文缩写:
产品介绍background:
Metalloprotease that may play a role in the degradation of COMP. Binds 1 zinc ion per subunit. pH dependence: Optimum pH is between 7.5 and 9.5. [Subcellular location] Secreted, extracellular space, extracellular matrix (By similarity). Note=Also found associated with the external cell surface[Tissue specificity] Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments. Up-regulated in articular cartilage and synovium from arthritis patients.
Function:
Metalloprotease that may play a role in the degradation of COMP.
Subunit:
Interacts with COMP.
Subcellular Location:
Secreted, extracellular space, extracellular matrix. Note=Also found associated with the external cell surface.
Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments.
Post-translational modifications:
N-glycosylated.
O-glycosylated proteoglycan. Contains chondroitin sulfate (By similarity).
May be cleaved by a furin endopeptidase (By similarity). The precursor is sequentially processed.
Similarity:
Contains 1 disintegrin domain.
Contains 1 peptidase M12B domain.
Contains 1 PLAC domain.
Contains 8 TSP type-1 domains.