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FITC标记的β淀粉样蛋白前体蛋白结合蛋白2抗体
品名:
FITC标记的β淀粉样蛋白前体蛋白结合蛋白2抗体
货号:
DL-1235
英文:
Anti-APPBP2/FITC
英文缩写:
产品介绍background:
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008].
 
Function:
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
 
Subunit:
Binds APP. 
 
Subcellular Location:
Nucleus. Cytoplasm
 
Post-translational modifications:
Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.